Browsing by Author "Tsantes, Argirio E."
Now showing items 1-19 of 19
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Angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism and circulating ACE levels are not associated with outcome in critically ill septic patients
Tsantes, Argirio E.; Tsangaris, I.; Kopterides, Petros; Nikolopoulos, Georgios K.; Kalamara, Eleni; Antonakos, Georgios; Kapsimali, Violetta; Gialeraki, Argiri; Dimopoulou, Ioanna; Orfanos, S.; Dima, Kleanthi; Travlou, Anthi S.; Armaganidis, Apostolos (2012)Background: In critically ill patients independent studies have shown contradictory findings regarding the prognostic significance of the D/D genotype of the I/D angiotensin converting enzyme (ACE) polymorphism. The study ...
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Assessing the secular trends in the transmission of HIV in Greece
Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Masgala, Aikaterini; Paraskeva, D. (2005)Objective: To evaluate the current trends in HIV transmission in Greece. Methods: A retrospective study of HIV infected individuals reported to the Hellenic Center for Infectious Diseases Control (HCIDC) was conducted. ...
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The association between plasminogen activator inhibitor type 1 (PAI-1) levels, PAI-1 4G/5G polymorphism, and myocardial infarction: A mendelian randomization meta-analysis
Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Tsangaris, I.; Tsiara, Chrissa G.; Kopterides, Petros; Vaiopoulos, A.; Kapsimali, Violetta; Bonovas, Stefanos; Tsantes, Argirio E. (2014)Background: The circulating levels of plasminogen activator inhibitor type 1 (PAI-1) are increased in individuals carrying the 4G allele at position -675 of the PAI-1 gene. In turn, overexpression of PAI-1 has been found ...
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Association between the plasminogen activator inhibitor-1 4G/5G gene polymorphism and ischemic stroke; A meta-analysis.
Nikolopoulos, Georgios K.; Tsantes, Argirio E.; Bagos, Pantelis G.; Tsiara, Chrissa G.; Mantzios, Georgios P.; Kapsimali, Violetta; Pappa, Vassiliki; Travlou, Anthi S. (2006)
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Association between the plasminogen activator inhibitor-1 4G/5G polymorphism and venous thrombosis
Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Rapti, E.; Mantzios, Georgios P.; Kapsimali, Violetta; Travlou, Anthi S. (2007)The effect of the 675 insertion/deletion (4G/5G) polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene on the risk of venous thromboembolism (VTE) remains controversial. In this study, we performed a meta-analysis ...
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Cost-effectiveness of leucoreduction for prevention of febrile non-haemolytic transfusion reactions
Tsantes, Argirio E.; Kyriakou, Elias; Nikolopoulos, Georgios K.; Stylos, D.; Sidhom, M.; Bonovas, Stefanos; Douramani, Panagiota; Kalantzis, Dimitrios; Kokoris, Styliani; Valsami, S.; Stamoulis, K.; Politou, M.; Foudoulaki-Paparizos, Leontini (2014)Background. The cost-effectiveness of universal leucoreduction of blood components remains unclear. When using leucoreduced red blood cells, the decrease in the rate of febrile non-haemolytic transfusion reactions (FNHTR) ...
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Direct evidence for normalization of platelet function resulting from platelet count reduction in essential thrombocythemia
Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Tsirigotis, P.; Zoi, K.; Zomas, A.; Kapsimali, Violetta; Kopterides, Petros; Chondropoulos, Spyros; Dervenoulas, John; Mantzios, Georgios P. (2011)Essential thrombocythemia is characterized by persistent elevation and functional disturbances of platelets. Both the platelet function analyzer-100 (PFA-100) collagen-epinephrine (CEPI) cartridge and aggregometry with ...
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Effect of angiotensin converting enzyme gene I/D polymorphism and its expression on clinical outcome in acute respiratory distress syndrome
Tsantes, Argirio E.; Kopterides, Petros; Bonovas, Stefanos; Bagos, Pantelis G.; Antonakos, Georgios; Nikolopoulos, Georgios K.; Gialeraki, Argiri; Kapsimali, Violetta; Kyriakou, Elias; Kokoris, Styliani; Dima, Kleanthi; Armaganidis, Apostolos; Tsangaris, I. (2013)Background. The role of the D allele of the angiotensin-converting enzyme (ACE) gene I/D polymorphism in the clinical outcomes of patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS) remains ...
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The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis
Tsantes, Argirio E.; Tsangaris, I.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Kopterides, Petros; Antonakos, Georgios; Dimopoulou, Ioanna; Vrioni, G.; Kapsimali, Violetta; Dima, Kleanthi; Armaganidis, Apostolos; Travlou, Anthi S. (2010)Background. There is considerable evidence that elevated plasma homocysteine levels are associated with a prothrombotic milieu, whereas activation of the coagulation cascade is an important component of the pathogenesis ...
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The effect of plasma homocysteine levels on clinical outcomes of patients with acute lung injury/acute respiratory distress syndrome
Tsangaris, I.; Tsantes, Argirio E.; Bagos, Pantelis G.; Nikolopoulos, Georgios K.; Kroupis, C.; Kopterides, Petros; Dimopoulou, Ioanna; Orfanos, S.; Kardoulaki, A.; Chideriotis, S.; Travlou, Anthi S.; Armaganidis, Apostolos (2009)Background: Several reports have shown that homocysteine promotes thrombosis by disturbing the procoagulant-anticoagulant balance, whereas alterations in coagulation and fibrinolysis have been suggested as important ...
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The effect of the plasminogen activator inhibitor-1 4G/5G polymorphism on the thrombotic risk
Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Bonovas, Stefanos; Kopterides, Petros; Vaiopoulos, G. (2008)Plasminogen activator inhibitor (PAI-1), is the central component of the fibrinolytic system. A deletion/insertion (4G/5G) polymorphism in the promoter region of the PAI-1 gene has been correlated with levels of plasma ...
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Epidemiology of aids defining conditions in Greece
Masgala, Aikaterini; Nikolopoulos, Georgios K.; Tsantes, Argirio E.; Paraskeva, D. (2004)Objective: To examine the secular trends of all AIDS opportunistic infections to occur first (Ols) in Greece, by year, by gender and by mode of transmission. Methods: The study included all AIDS defining conditions reported ...
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HIV/AIDS: Recent advances in antiretroviral agents
Nikolopoulos, Georgios K.; Bonovas, Stefanos; Tsantes, Argirio E.; Sitaras, N. M. (2009)Despite the considerable progress in antiretroviral therapy, the eradication of HIV-1 remains unfeasible. Therefore, novel agents are under investigation. The aim of this review is to summarize the conventional compounds, ...
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Integrin, alpha 2 gene C807T polymorphism and risk of ischemic stroke: A meta-analysis
Nikolopoulos, Georgios K.; Tsantes, Argirio E.; Bagos, Pantelis G.; Travlou, Anthi S.; Vaiopoulos, G. (2007)Introduction: Platelet adhesion to fibrillar collagen via the membrane glycoprotein (GP) Ia/IIa (α2β1), is a crucial event in the pathogenesis of arterial occlusive disorders. The C807T single nucleotide polymorphism of ...
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Laboratory Assessment of the Anticoagulant Activity of Dabigatran
Kyriakou, Elias; Ikonomidis, Ignatios; Stylos, D.; Bonovas, Stefanos; Papadakis, I.; Nikolopoulos, Georgios K.; Kokoris, Styliani; Kalantzis, Dimitrios; Economopoulou, Christine; Kopterides, Petros; Lekakis, John; Tsantes, Argirio E. (2015)Background: Our aim was to identify laboratory assays in order to assess the anticoagulant effects of dabigatran etexilate (DE). Methods: Twenty patients with nonvalvular atrial fibrillation treated on DE (110 mg per os ...
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Lack of association between the platelet glycoprotein Ia C807T gene polymorphism and coronary artery disease: A meta-analysis
Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Vaiopoulos, G.; Travlou, Anthi S. (2007)Background: The platelet-collagen receptor, glycoprotein (GP) la/lla plays a crucial role in the adhesion of platelets to fibrillar collagen, an event contributing to the pathogenesis of thrombosis. The C807T polymorphism ...
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Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of ischemic stroke: A meta-analysis
Tsantes, Argirio E.; Nikolopoulos, Georgios K.; Bagos, Pantelis G.; Tsiara, Chrissa G.; Kapsimali, Violetta; Travlou, Anthi S.; Vaiopoulos, G. (2007)This study investigated the hypothesis that the insertion/deletion (4G/5G) polymorphism of the plasminogen activator inhibitor type-1 gene affects the risk for ischemic stroke, since results concerning this association ...
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Reference ranges of thromboelastometry in healthy full-term and pre-term neonates
Sokou, R.; Foudoulaki-Paparizos, Leontini; Lytras, Theodoros; Konstantinidi, Aikaterini; Theodoraki, M.; Lambadaridis, Ioannis; Gounaris, Antonis; Valsami, S.; Politou, M.; Gialeraki, Argiri; Nikolopoulos, Georgios K.; Iacovidou, Nicoletta; Bonovas, Stefanos; Tsantes, Argirio E. (2017)Rotational thromboelastometry (ROTEM) is an attractive method for rapid evaluation of hemostasis in neonates. Currently, no reference values exist for ROTEM assays in full-term and pre-term neonates. Our aim was to establish ...
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Surveillance data on paediatric HIV infection and AIDS in Greece.
Nikolopoulos, Georgios K.; Konte, Vasileia; Masgala, Aikaterini; Eleni, E.; Tsantes, Argirio E.; Paraskeva, D. (2004)In Greece, HIV/AIDS surveillance is conducted by the Hellenic Centre for Infectious Diseases Control. The AIDS case reporting system was implemented in 1984, followed by notification of HIV infections in 1998. This article ...